A suite of high-resolution, targeted quantitative, and GC-MS platforms supports metabolomics, lipidomics, proteomics, and small-molecule analysis across a wide range of experimental needs.
Thermo Scientific Eclipse Orbitrap
Core instrumentation
The facility combines a range of instrument types so analytical platforms can be matched to the goals of each study, from untargeted high-resolution profiling and structural characterization to sensitive targeted quantitation.
Thermo Scientific · Two instruments
Two high-resolution Tribrid Orbitrap systems supporting advanced proteomics, untargeted metabolomics, and complex MS/MS workflows.
Deep proteomics · Advanced MS/MS · Structural characterization
Thermo Scientific
High-resolution accurate-mass LC-MS platform used for metabolomics profiling, accurate mass analysis and samples and other routine high-resolution workflows.
HRAM profiling · Metabolomics · Routine high-resolution workflows
Agilent
Quadrupole time-of-flight mass spectrometer used for large and small-molecule accurate-mass analysis, untargeted metabolomics, and MS/MS-based compound characterization.
Untargeted metabolomics. Small molecules · MS/MS characterization
Agilent
High-sensitivity QTOF platform used for accurate-mass profiling and characterization of peptides and other small molecules in complex matrices.
High-sensitivity profiling · Untargeted metabolomics · Accurate mass
Thermo Scientific
Triple-quadrupole LC-MS/MS platform used for sensitive targeted assays and quantitative analysis of defined small-molecule panels.
Targeted assays · Small-molecule quantitation · High-sensitivity LC-MS/MS
Agilent
High-sensitivity triple-quadrupole system supporting quantitative LC-MS/MS assays across a wide range of small-molecule and lipid applications.
Targeted assays · Small-molecule quantitation High-sensitivity LC-MS/MS
Agilent
Established quantitative LC-MS/MS platform used for targeted small-molecule measurements and mature analytical workflows.
Targeted assays · Small-molecule quantitation · High-sensitivity LC-MS/MS
Agilent
Gas chromatography–mass spectrometry platform providing complementary analysis for compounds better suited to GC separation, including alcohols, aromatic compounds, and fatty acid methyl esters (FAMEs).
GC-MS · Volatile and derivatized compounds · FAMEsSupporting infrastructure
Instrumentation is supported by dedicated chromatography, sample-preparation, data-analysis, and laboratory infrastructure within the core.
Dedicated UHPLC systems support analytical separations across the LC-MS platforms. An Agilent 1200 HPLC is also maintained for offline fractionation and other preparative applications.
Dedicated wet-lab space supports solid phase and liquid-liquid extraction, centrifugation, vacuum concentration, nitrogen drying, lyophilization, protein digestion, and other sample-preparation workflows.
Dedicated computing and laboratory servers support metabolomics and proteomics processing, data analysis, compound annotation, data storage, and instrument-specific software workflows.
Platform selection depends on the biological question, analyte class, required sensitivity, quantitative requirements, and whether the study is targeted or discovery-driven. The core can help select the appropriate analytical approach before samples are submitted.